Differences in the progression of liver disease in male and female rats induced by TAA: considerations in the development of pharmacological therapies
Introduction and Objectives: Thioacetamide (TAA) is a hepatotoxic agent that causes fibrosis, cirrhosis, and cancer.Various doses and regimens of TAA have been tested in different murine models to validate hepatoprotective compounds.To date, only two studies have reported differences in TAA susceptibility according to sex in murine models.To compar